Overall it is very unlikely that there will be any overall changes. Vincenzo Nibali has established a nice cushion between himself and his rivals. 2012 was the last time Nibali rode the Tour when he finished third behind Bradley Wiggins and Chris Froome. He will be difficult to beat. Peter Sagan will probably be even more difficult to beat in the Green Jersey competition as he further stretched his lead yesterday.
The Steephill site has great coverage and links for the Tour.